Ing Ind - Inf (Mag.)(ord. 270) - MI (486) ENGINEERING PHYSICS - INGEGNERIA FISICA
054849 - DIFFUSE OPTICAL TOMOGRAPHY
054345 - BIOPHOTONICS (C.I.)
054850 - OPTICAL MICROSCOPY
Introduce the student to the fundamentals of optical imaging and tomography at the micro/nano-scale to the macroscopic level, presenting the physical basis, introducing the mathematical tools, discussing instrumental implementations, togetther with photonics advancements, and describing examples of applications, with particular emphasis on biophysical and biomedical topics.
Risultati di apprendimento attesi
- Knowledge and understanding
The students will improve knowledge and understanding on wave physics, diffraction and diffusion, light-matter interaction, linear algebra and inverse problems, with specific application to the problem of optical microscopy and optical tomography in diffusive media.
- Apply knowledge and understanding
The students will be able to design autonomously an optical system for microscopy and imaging. The students will be able to evaluate the resolution and contrast in optical microscopy and diffuse tomography systems. The students will be challenged to solve – in the project activity – a problem of tomographic reconstruction implying the application of knowledge on the physics of diffuse optics, modelling of real photonics systems and methods for solving inverse problems.
- Making Judgements
Given a specific optical imaging system, the students will be able to precisely analyse the resolution and contrast.
The students will be required to judge the plausibility of their own project results as well as, in common discussions, of the outcomes of other teams.
- Lifelong learning skills
The students will be capable to understand how to take into account, and how to overcome the effects of diffraction and diffusion in a biological sample.
The students will be faced with the key difference between theoretical models and practical implementation, as well as the ability of problem solving, team-working and workflow organization.
Optical microscopy and nanoscopy:
Point spread function in an optical microscope and 3D imaging theory.
Diffuse Optical Tomography in the linear (Born approximation) and non-linear regime.
Applications and new perspectives.
Basic knowledge on wave physics, linear algebra, diffusion equation for highly scattering media.
Knowledge and understanding of the Fourier Transform.
Modalità di valutazione
The final assessment will be based on a written test with open questions on the topics of the course and of the project activity.
Jerome Mertz, Introduction to Optical Microscopy, Editore: Cambridge University Press, Anno edizione: 2019
Lihong V. Wang, Hsin-I. Wu, Biomedical optics: principles and imaging, Editore: John Wiley & Sons, Anno edizione: 2012
Tipo Forma Didattica
Ore di attività svolte in aula
Ore di studio autonome
Laboratorio Di Progetto
Informazioni in lingua inglese a supporto dell'internazionalizzazione
Insegnamento erogato in lingua
Disponibilità di materiale didattico/slides in lingua inglese
Disponibilità di libri di testo/bibliografia in lingua inglese
Possibilità di sostenere l'esame in lingua inglese