Risorse bibliografiche
Risorsa bibliografica obbligatoria
Risorsa bibliografica facoltativa
Scheda Riassuntiva
Anno Accademico 2019/2020
Scuola Scuola di Ingegneria Industriale e dell'Informazione
Cfu 5.00 Tipo insegnamento Monodisciplinare
Docenti: Titolare (Co-titolari) Costantino Maria Laura

Corso di Studi Codice Piano di Studio preventivamente approvato Da (compreso) A (escluso) Insegnamento
Ing Ind - Inf (1 liv.)(ord. 270) - MI (363) INGEGNERIA BIOMEDICA*AZZZZ096208 - BIOMACHINES (WITH LABORATORY)

Obiettivi dell'insegnamento

The course is aimed at providing the students the proper methodologies to design and evaluate the performances of heart valve prostheses and extracorporeal circulation devices. After a short introduction recalling the basic physiology and energetics of the heart and the circulatory system, the main causes of blood hemolysis and coagulation will be discussed. Criteria about how to optimise, adjust and evaluate the performances of the deviced will be given. The students will acquire the ability to solve problems related to the interaction of the devices with blood. Moreover the course aims at bringing the students to make autonomous judgements about the possible solutions to be adopted.

Along the course clinical applications/implantation procedure and devices will be shown to the students either in the form of videos/slides or by showing real commercial devices.

Students will be brought to the Laboratory to observe and understand how experimental testing of the devices focused during the course is performed, so as to enhance understanding of the taught theory.

Risultati di apprendimento attesi

At the end of the course the students are expected to possess both know-how and know-why about the blood contacting devices and prostheses working conditions, constraints and design specifications.

With reference to the Dublin Descriptors listed herunder:

DD1 - Knowledge and understanding;
DD2 - Applying knowledge and understanding;
DD3 - Making judgements;
DD4 - Communication skills;
DD5 - Learning skills; 

the students are expected to develop and acquire abilities to meet all the Descriptors, namely applied to: 

- knowledge of the main concepts about the design constraints and specifications of the artificial internal organs or life support

systems focused during the course;

- knowledge and understanding of the main physical, mechanical, and chemical phenomena taking place in the devices;

- knowledge to perform calculations to design, quantify, and evaluate, the performances of the devices;

- ability to develop, judge and apply patient specific approaches to the design of artificial systems and know how to optimize the

interaction with the living organism;

- development of skills to face and communicate/promote innovation in this field of biomedical engineering.

Argomenti trattati

The course is aimed at teaching design and evaluation criteria of artificial heart valve prostheses and extracorporeal circulation devices.

More specifically, the main subjects are the following:

- Survey  about cardiovascular system's functional anatomy and  physiology;

- Interaction between the cardiovascular and the artificial systems: hemolysis and coagulation;

- Design and evaluation criteria of mechanical and biological prosthetic heart valves;

- Design criteria for extracorporeal circuit devices and choice of the optimal vascular access;

- Layout of the extracorporeal circuit;

- Design and optimization of extra-corporeal blood pumps;

- Design of blood heat exchangers;

-Design of extracorporeal blood oxygenation devices;

-Design of blood filters.

International standards prescription related to the testing and the production of prosthetic heart valves and extracorporeal circulation devices will also be presented.

Practical class activities will deal with the solution of problems related to the design and setting of the studied Biomachines. Laboratory activities will be planned to allow the students to focus the experimental evaluation of the studied devices and the related instrumentation.


Attendance of the course Biomeccanica, is strongly advised. However, the main concepts from this course will be recalled at the beginning of the Biomachines (with Laboratory) course, and anytime these concepts should be essential to ease and deepen students' knowledge. 

Modalità di valutazione

The final exam will consist in  a written test  which, in specific cases, can be followed by an oral exam.

The students will be evaluated based on their capacity to answer theoretical questions about the subjects taught during the course

and to frame them in a wider scenario. More specifically skills about knowledge and understanding and communications, will be

evaluated. Moreover, the student will be evaluated based on his/her capacity to establish connections among the different subjects

dealt with during the course, and among the course and the other courses attended. More specifically, students' skills in applying

knowledge and understanding to problem solving, in making judgements about the possible technical choices, and in communication

modalities to explain and assess the validity of the chosen methods, will be evaluated (as per DD1, DD2, DD3, DD4, DD5).

Risorsa bibliografica facoltativaMaria Laura Costantino, Notes from the Course of Biomachines (with Laboratory)

The notes are available in pdf format on the Beep page of the course.

Software utilizzato
Nessun software richiesto

Forme didattiche
Tipo Forma Didattica Ore di attività svolte in aula
Ore di studio autonome
Laboratorio Informatico
Laboratorio Sperimentale
Laboratorio Di Progetto
Totale 50:00 75:00

Informazioni in lingua inglese a supporto dell'internazionalizzazione
Insegnamento erogato in lingua Inglese
Disponibilità di materiale didattico/slides in lingua inglese
Possibilità di sostenere l'esame in lingua inglese
Disponibilità di supporto didattico in lingua inglese
schedaincarico v. 1.10.0 / 1.10.0
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