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| Academic Year |
2024/2025 |
| Name |
Dott. - MI (1380) Ingegneria dell'Informazione / Information Technology |
| Programme Year |
1 |
| ID Code |
062775 |
| Course Title |
HIGH RESOLUTION ELECTRONIC MEASUREMENTS IN NANO-BIO SCIENCE |
| Course Type |
MONO-DISCIPLINARY COURSE |
| Credits (CFU / ECTS) |
5.0 |
| Course Description |
The course will focus on :
- How to use and possibly to design dedicated instrumentation for the measurement of currents, voltages, impedance and noise with the state-of-the-art sensitivity. The course will introduce the best commercial instrumentation and the best circuit architectures, the design considerations for maximum resolution and their achievable performance together with the specific aspects to be taken into account when integrating the full instrument on a single chip.
- How to perform impedance spectroscopy measurements with sub-attofarad resolution and nanoscale position resolution .
The course will introduce capacitance measurements tecniques and impedance spectroscopy applications, eventually coupled with Atomic Force Microscopes to complement the electrical information with a position information of nanometric precision.
- How to perform electrical measurements on biomolecules in-vitro in the presence of physiological saline solution. In particular how to make ohmic contacts (DC electrical access) to the liquid, how to use the electrolite as conformal conductive electrode and how to prevent DC conduction through metal-liquid interfaces (AC electrical access). .
The course will discuss how to manage the electrical signals extracted from neutral molecules via electrochemical measurements with 3 electrodes, the electronic circuits to interface electrodes whose size can be as small as few tens of nanometer square and various applications in the biological domain from olfactory receptors, to cathecolamine exocitosis, to cell counting, etc.
- How to use electronic noise as a signal to access the physical properties of matter at the nanoscale .
The course will recall the most advanced methods to measure very low noise levels, even lower than the input noise of standard instrumentation. It will then highlight, through examples, the tecniques of noise characterisation to extract physical quantities: from telegraph noise to electron spin, from shot noise to dielectric relaxation times, showing the importance of adeguate instrumentation like the correlation spectum analyzer. |
| Scientific-Disciplinary Sector (SSD)
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SSD Code
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SSD Description
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CFU
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ING-INF/01
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ELECTRONIC ENGINEERING
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5.0
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Alphabetical group
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Name
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Teaching Assignment Details
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From (included)
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To (excluded)
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A
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ZZZZ
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Sampietro Marco, Ferrari Giorgio, Zanetto Francesco
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